Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Incidence and Antibiotic Susceptibility Pattern of Bacterial Isolates from Wound Infections in a Tertiary Hospital in Nigeria

Aisha Mohammed, Gbonjubola O Adeshina , Yakubu K Ibrahim

Department of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria, Nigeria;

For correspondence:- Gbonjubola Adeshina Email: dotunkele@yahoo.com Tel:+2348037880000

Received: 18 October 2012 Accepted: 17 June 2013 Published: 23 August 2013

Citation: Mohammed A, Adeshina GO, Ibrahim YK. Incidence and Antibiotic Susceptibility Pattern of Bacterial Isolates from Wound Infections in a Tertiary Hospital in Nigeria. Trop J Pharm Res 2013; 12(4):617-621 doi: 10.4314/tjpr.v12i4.26

© 2013 The authors.
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Abstract

Purpose: To investigate the incidence of different bacteria isolates in 150 wound infections in Aminu Kano Teaching Hospital, Kano, Nigeria and their antibacterial susceptibility patterns.

Methods: Wound swab samples were collected from general culture bench of the Microbiology Department, after obtaining consent from the hospital’s Medical Advisory Committee, and cultured for bacterial isolates. The isolates were characterized and identified by standard microbiological methods. Antibiotic susceptibility testing was carried out using Kirby-Bauer-CLSI modified Disc Agar Diffusion technique.

Results: Out of the 150 specimens collected, 82 % were infected with bacteria made up predominantl of Staphylococcus aureus (22 %), Pseudomonas aeruginosa (19.9 %), Citrobacter spp (15 %), Escherichia coli (14.7 %) and Proteus mirabilis (14.5 %). In vitro antibiotic susceptibility tests showed that Pseudomonas aeruginosa was susceptible to ceftazidime, ciprofloxacin and gentamicin while the enteric bacteria were generally more resistant to ceftazidime, gentamicin and ciprofloxacin.

Conclusion: The findings show that there is a high rate of wound infection in Kano, Nigeria and that antibiotic-resistant bacteria are present in the wound sites.

Keywords: Wound infection , Antibiotic, Susceptibility, Bacterial resistance